产品名称:重组小鼠源blood vessel内皮生长因子,His-标签(VEGF164)

产品英文名称:Mouse VEGF164 Protein, His tag

货号:PRP1301

产品特点&优势:
通过LAL法测定,每微克蛋白里内毒素含量<0.1 EU。

重组小鼠源blood vessel内皮生长因子,His-标签(VEGF164)产品背景:
Mouse Vascular endothelial growth factor (VEGF or VEGFA), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the PDGF/VEGF growth factor family that is characterized by a cystine knot structure formed by eight conserved cysteine residues. Alternately spliced isoforms of 120, 164 and 188 aa found in mouse. VEGF binds the type I transmembrane receptor tyrosine kinases VEGF R1 (also called Flt1) and VEGF R2 (Flk/KDR) on endothelial cells.Although affinity is highest for binding to VEGF R1, VEGF R2 appears to be the primary mediator of VEGF angiogenic activity. VEGF is required during embryogenesis to regulate the proliferation, migration, and survival of endothelial cells.It may play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis.

序列:
氨基酸序列来源于:小鼠源VEGF164 (Ala27-Arg190) (Q00731-2) 表达的蛋白片段。

标签:His

活性:
Testing in Progress

蛋白长度:
重组小鼠 VEGF165 由165个氨基酸组成,预测分子量为19.4 KD。

分子:
VEGF164

检测指标:
VEGF164

产品形式:冻干粉,冻干缓冲液为无菌的20 mM Tris,150 mM NaCl,pH 8.0。

重组小鼠源blood vessel内皮生长因子,His-标签(VEGF164)产品注意事项:
开盖使用前,请先离心。本产品为冻干粉,推荐用该产品配套的Reconstitution Buffer进行复溶,且浓度不低于106 μg/mL。客户可根据后续的实验需求,进行进一步的稀释。

警告:
本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。