产品名称:重组人骨形态发生蛋白-7(BMP-7)

产品英文名称:Human BMP-7 Protein

货号:PRP1946

产品特点&优势:
通过LAL法测定,每微克蛋白里内毒素含量<0.1 EU。

重组人骨形态发生蛋白-7(BMP-7)产品背景:
Bone morphogenetic protein 7 (BMP-7) is a multifunctional ligand protein belongs to the TGF-β family. BMP-7 is involved in regulating the proliferation, invasion, and migration of cancer cells, and is associated with various human tumors. BMP-7 binds to ALK2 or ACVR2A/BMPR2 excitation signals, which are regulated and terminated by SMADs. BMP-7 is involved in the BMP-7 Smad1/5/9 signaling pathway and is associated with the epithelial mesenchymal transition (EMT) process. BMP-7 also eliminates vascular inflammation, maintains vascular integrity, weakens vascular calcification, and stimulates in situ phosphorylation deposition. The growth factor domain of human BMP-7 shares 98% aa sequence identity with mouse and rat BMP-7.

序列:
氨基酸序列来源于:人源 BMP7(Met315-His431) (P18075) 表达的蛋白片段。

标签:无标签

活性:
Testing in Progress

蛋白长度:
重组人BMP7由117个氨基酸组成,预测分子量为13.2 KD。

分子:
BMP-7

检测指标:
BMP-7

产品形式:冻干粉,冻干缓冲液为无菌的20 mM Tris-HCl,250 mM NaCl,pH 8.0。

重组人骨形态发生蛋白-7(BMP-7)产品注意事项:
开盖使用前,请先离心。本产品为冻干粉,推荐用该产品配套的Reconstitution Buffer进行复溶,且浓度不低于100 μg/mL。客户可根据后续的实验需求,进行进一步的稀释。

警告:
本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。