产品名称:重组小鼠成纤维细胞生长因子4(FGF-4)

产品英文名称:Mouse FGF-4 Protein

货号:PRP1305

产品特点&优势:
通过LAL法测定,每微克蛋白里内毒素含量<0.1 EU。

重组小鼠成纤维细胞生长因子4(FGF-4)产品背景:
Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development.

序列:
氨基酸序列来源于:小鼠FGF4 (P11403) (Ser67-Leu202) 表达的蛋白片段。

标签:无标签

活性:
Testing in Progress

蛋白长度:
重组人 MIF 由120个氨基酸组成,预测分子量为13.1 KD。

分子:
FGF-4

检测指标:
FGF-4

产品形式:冻干粉,冻干缓冲液为无菌的20 mM Tris,50 mM NaCl,pH 8.0。

重组小鼠成纤维细胞生长因子4(FGF-4)产品注意事项:
开盖使用前,请先离心。本产品为冻干粉,推荐用该产品配套的Reconstitution Buffer进行复溶,且浓度不低于100 μg/mL。客户可根据后续的实验需求,进行进一步的稀释。

警告:
本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。