产品名称:重组人干扰素α2a(IFN-α2a)

产品英文名称:Human IFN-α2a Protein

货号:PRP1237

产品特点&优势:
通过LAL法测定,每微克蛋白里内毒素含量<1 EU。

重组人干扰素α2a(IFN-α2a)产品背景:
At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes only differ in their sequences by one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end. IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interferons (IFNs) are well-known cytokines that exert antiviral activity, antitumor activity, and immunomodulatory effects.

序列:
氨基酸序列来源于:人源 IFN-α2a (Cys24-Glu188) (P01563) 表达的蛋白片段。

标签:无标签

活性:
使用TF-1细胞进行细胞毒性测定。该效应的ED50为0.3301 ng/mL。

蛋白长度:
重组人IFN-α2a由166个氨基酸组成,预测分子量为19.4 kDa.

分子:
IFN-α2a

检测指标:
IFN-α2a

产品形式:冻干粉,冻干缓冲液为无菌的20 mM Tris, 150 mM NaCl, pH8.0.

重组人干扰素α2a(IFN-α2a)产品注意事项:
开盖使用前,请先离心。本产品为冻干粉,推荐用该产品配套的Reconstitution Buffer进行复溶,且浓度不低于100 μg/mL。客户可根据后续的实验需求,进行进一步的稀释。

警告:
本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。