产品名称:重组人4-1BB配体,His-标签(无动物源)(4-1BBL)

产品英文名称:Human 4-1BBL Protein, His tag (Animal-Free)

货号:PRP1217

产品特点&优势:
通过LAL法测定,每微克蛋白里内毒素含量<0.05 EU。

重组人4-1BB配体,His-标签(无动物源)(4-1BBL)产品背景:
4-1BB ligand (4-1BBL) is a type II transmembrane protein that is part of the tumor necrosis factor (TNF) ligand family. As an inducible co-stimulatory molecule, it presents on several antigen presenting cell (APC) types, including B cells, macrophages and DCs. The interactions between 4-1BB and 4-1BBL trigger pleiotropic effects on the immune response including antigen presenting process, proliferation of CD4 and CD8 positive T-cells, as well as cytokine secretion from T-cells through NFκB, c-Jun, and p38 downstream signal pathways activation.Therefore, 4-1BB and 4-1BBL are recently used for the immunotherapy of cancer.

序列:
氨基酸序列来源于:人源4-1BBL Protein (Arg71-Glu254) (P41273)

标签:His

活性:
Measure by its ability to induce IL-8 secretion in human PBMCs. The ED?? for this effect is 1-5 ng/mL.

蛋白长度:
重组人4-1BBL蛋白由184个氨基酸组成,预测分子量为20.4 KD。

分子:
4-1BBL

检测指标:
4-1BBL

产品形式:冻干粉,冻干缓冲液为无菌的PBS,pH 7.4。

重组人4-1BB配体,His-标签(无动物源)(4-1BBL)产品注意事项:
开盖使用前,请先离心。本产品为冻干粉,推荐用该产品配套的Reconstitution Buffer进行复溶,且浓度不低于100 μg/mL。客户可根据后续的实验需求,进行进一步的稀释。

警告:
本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。